10 Best ADCs To Duo With Annie In League of Legends

Annie support might fly under the radar, but with the right ADC, she can turn bot lane into a kill lane from the moment she hits level 2. With strong burst damage, a reliable stun, and the threat of a game-changing Tibbers engage at level 6, Annie brings serious pressure to lane. She pairs best with ADCs who can follow up on her crowd control or help poke down enemies for all-ins. In this article, we’ll go over the 10 best ADCs to duo with Annie support in League of Legends, focusing on synergy, lane dominance, and how to turn a single stun into a winning fight.

#10: Jinx

Jinx pairs well with Annie support thanks to Annie’s ability to control fights and set up easy kills. Annie’s stun makes it simple for Jinx to land her Flame Chompers! and follow up with rockets for big poke or all-in damage. Once Annie hits level 6, a Tibbers drop combined with Jinx’s damage can instantly swing a fight, and if Jinx gets a kill, she’s off to the races with her passive. This duo shines in chaotic fights where Annie locks targets down and Jinx resets her way to a teamfight win.

#9: Zeri

Zeri and Annie make a strong duo where Annie handles the setup and frontline while Zeri follows up with her mobility and sustained damage. Annie’s reliable stun helps Zeri land early trades more safely and gives her the space she needs to ramp up in fights. Once Annie hits level 6, a well-timed Tibbers engage can lock down multiple enemies, allowing Zeri to activate her ult and zip through the fight with confidence. It’s a high-speed, high-damage combo that thrives in messy skirmishes and teamfights.

#8: Draven

Draven and Annie form an aggressive, snowball-heavy lane that’s built for early kills. Annie’s stun gives Draven the perfect setup to land his Spinning Axes and go all-in without fear. Her burst damage also helps secure quick trades, making it easier for Draven to cash in on his passive. Once level 6 hits, a full Tibbers combo followed by Draven’s ult can delete most bot lane duos in seconds. This duo is perfect for players who want nonstop pressure and love taking control of the lane from the start.

#7: Samira

Samira and Annie are a deadly combo that thrives on quick engages and full-on brawls. Annie’s stun—whether it’s from a charged Q or a Tibbers drop—gives Samira exactly what she needs to instantly trigger her passive and follow up with a full combo. In lane, Annie’s poke and crowd control help Samira stay aggressive and build stacks safely. Once they hit level 6, a Tibbers engage often leads to Samira diving in with Inferno Trigger for a quick double kill. It’s a high-risk, high-reward lane that rewards bold plays and clean coordination.

#6: Caitlyn

Caitlyn and Annie make a strong poke-and-punish duo that controls the lane with ease. Annie’s stun sets up perfect opportunities for Caitlyn to land Yordle Snap Traps, guaranteeing a headshot and follow-up burst. Their combined poke makes it hard for enemies to walk up, and once Annie hits level 6, a Tibbers engage into trap combo can melt even the tankiest opponents. This pairing is all about zoning, strong laning presence, and punishing mistakes with hard-hitting follow-ups.

#5: Ezreal

Ezreal and Annie make a great duo for safe, poke-heavy lanes with strong burst potential. Annie’s stun helps peel and set up trades, giving Ezreal time to land Mystic Shots and poke from a distance. While Ezreal plays it safe and scales, Annie controls the pace of the lane with her stun threat and surprise Tibbers engages. Once level 6 hits, Annie can go in with her full combo while Ezreal follows up with Trueshot Barrage for massive burst damage. It’s a smart, balanced lane that punishes overextensions and scales well into skirmishes.

#4: Vayne

Vayne and Annie make a solid duo where Annie handles the early pressure and setup, giving Vayne the space she needs to scale. Annie’s point-and-click stun is perfect for helping Vayne land Condemn or secure safe trades in the early game. Her burst can also scare enemies off when they try to engage on Vayne. Once level 6 hits, Annie can initiate with Tibbers and soak the frontline while Vayne activates Final Hour and cleans up from the back. This combo is all about protection, setup, and scaling into a late-game carry threat.

#3: Ashe

Ashe and Annie make a lane focused on control, poke, and back-to-back crowd control. Annie’s stun sets up easy Volley trades and slows, while Ashe’s constant auto-attack slows help Annie stay in range for follow-up damage. Once they hit level 6, their engage potential skyrockets—Ashe can lead with Enchanted Crystal Arrow from range, and Annie can instantly follow up with Tibbers for a devastating CC chain. This duo is perfect for punishing bad positioning and keeping enemies locked down long enough to secure clean kills.

#2: Jhin

Jhin and Annie are a burst-heavy duo that thrives on precise CC and high-damage combos. Annie’s stun sets up Jhin’s Deadly Flourish for an easy root, and her burst helps chunk enemies down quickly so Jhin can finish with his fourth shot. In lane, they can poke safely and punish any misstep with a full combo. Once they hit level 6, Annie can drop Tibbers for a massive AoE stun while Jhin follows up with Curtain Call to clean up kills from range. It’s a lane built around control, execution, and turning small openings into big leads.

#1: Miss Fortune

Miss Fortune is the best ADC to pair with Annie support thanks to their incredible synergy in both lane and teamfights. Annie’s stun—especially once she hits level 6—sets up the perfect moment for MF to channel Bullet Time without interruption. Even in the early game, Annie’s poke and zone control allow MF to land Double Up and Make It Rain for strong trades. When they engage together, Annie locks enemies down with Tibbers, and MF deletes them with her ult. It’s a deadly wombo-combo lane that’s easy to execute and insanely effective.

Conclusion

Annie support brings powerful crowd control, strong early burst, and game-changing engages—all of which become even more dangerous when paired with the right ADC. Whether you’re looking to chain CC with Jhin and Ashe, scale safely with Jinx and Vayne, or go all-in with Miss Fortune or Draven, Annie sets the stage for her ADC to shine. With just one charged stun or a perfectly timed Tibbers drop, she can completely turn the tide of a fight. If you’re looking to dominate bot lane with aggressive plays and reliable setups, these ADCs are the perfect partners for Annie’s explosive support style.