10 Best Prime Weapons In Warframe

In Warframe, the Tenno are the most formidable faction, wielding exceptional Warframes and weapons capable of annihilating enemies with devastating precision. Among these, Prime weapons stand out as elite versions of their standard counterparts, offering unique advantages that enhance gameplay and combat effectiveness.

Prime weapons often boast improved stats, such as increased damage, critical chance, or reload speed. Some even come with unique effects, like summoning an ethereal weapon on multi-kills. These upgrades make them indispensable for tackling Warframe’s toughest challenges. Players can acquire these coveted weapons by farming relics in-game or purchasing Prime Access packages for immediate access.

Whether you’re aiming to maximize damage output, excel in endgame missions, or simply showcase your mastery, Prime weapons are a must-have in your arsenal. In this article, we’ll delve into the 10 best Prime weapons available in Warframe, helping you decide which ones to prioritize for your next adventure. Let’s explore the pinnacle of Tenno firepower!

#10: Nikana Prime

The Nikana Prime is a melee weapon of choice for Tenno seeking a perfect blend of elegance and lethality. As the Prime version of the Nikana, it boasts increased base damage, critical chance, and status chance, making it one of the most versatile melee weapons in Warframe. Its high attack speed and impressive reach further enhance its effectiveness, allowing players to carve through enemies with ease.

What truly sets the Nikana Prime apart is its synergy with critical-focused builds, thanks to its exceptional critical multiplier. When paired with mods like Blood Rush and Weeping Wounds, this weapon becomes a powerhouse capable of shredding even the toughest foes. Its striking design also makes it a favorite for players who prioritize both performance and style in their Fashion Frame.

The Nikana Prime is obtained through relic farming, requiring specific parts from the game’s drop tables. With its devastating potential and stunning appearance, the Nikana Prime earns its place among the best Prime weapons in Warframe.

#9: Lex Prime

The Lex Prime is a powerhouse sidearm that delivers devastating single-shot damage with pinpoint accuracy. As the Prime variant of the Lex, this pistol retains its signature hard-hitting performance while offering improved critical chance, critical multiplier, and status chance, making it a formidable weapon in the hands of any Tenno.

Known for its ability to annihilate enemies with precision headshots, the Lex Prime is ideal for players who prefer a slow-firing yet immensely powerful secondary weapon. Its high base damage and critical stats make it perfect for scaling into late-game missions, especially when modded with Primed Target Cracker and Primed Pistol Gambit for maximum critical damage potential.

Although it has a slower fire rate and reload speed compared to other sidearms, these drawbacks are easily mitigated by its incredible stopping power. Whether you’re sniping enemies from a distance or delivering point-blank devastation, the Lex Prime is a reliable choice for both newcomers and veterans alike.

You can obtain the Lex Prime by farming the appropriate relics or trading with other players. Its combination of raw power and precision ensures its place among Warframe’s top Prime weapons.

#8: Galatine Prime

The Galatine Prime is a massive, heavy blade that excels at dealing overwhelming damage to large groups of enemies. As the Prime version of the Galatine, it features improved critical chance, critical multiplier, and base damage, making it a standout choice for Tenno who prefer melee combat with a devastating impact.

With its high base damage and exceptional critical stats, the Galatine Prime is perfect for builds focused on maximizing critical hits. When paired with mods like Blood Rush, Condition Overload, and Berserker Fury, this weapon becomes a whirlwind of destruction, capable of obliterating enemies in both normal missions and endgame content.

Its sweeping attacks and wide melee range make it particularly effective for clearing hordes of enemies in missions like Survival or Defense. While its slower attack speed may require adjustment, the sheer power of each swing compensates for this minor drawback.

Acquiring the Galatine Prime involves farming specific relics for its parts or trading with other players. With its unmatched power and imposing design, the Galatine Prime rightfully earns its spot as one of the best melee weapons in Warframe.

#7: Soma Prime

The Soma Prime is a quintessential rapid-fire weapon in Warframe, known for its high magazine capacity and exceptional critical potential. As the Prime variant of the Soma, it boasts enhanced critical chance, critical multiplier, and slightly improved reload speed, making it a top-tier weapon for shredding enemies with sustained firepower.

The Soma Prime excels in handling large groups of enemies, thanks to its rapid-fire nature and precise accuracy. Its incredible critical chance synergizes perfectly with mods like Point Strike and Vital Sense, enabling it to dish out massive damage when aimed at enemy weak points. When paired with a good Riven mod, this weapon can even rival some of the strongest rifles in the game.

While its lower base damage compared to other rifles might seem like a disadvantage, its high fire rate and critical stats make up for it, allowing it to sustain consistent damage output in any situation. The Soma Prime is particularly effective in crowd control scenarios, making it an excellent choice for missions like Defense or Survival.

The Soma Prime can be acquired by farming relics or trading with other players. Its balance of critical potential, magazine size, and smooth handling ensures its place among the best Prime weapons in Warframe.

#6: Boltor Prime

The Boltor Prime is a fan-favorite weapon in Warframe, revered for its ability to fire high-speed, armor-piercing bolts that deal massive damage. As the Prime variant of the Boltor, it offers improved base damage, critical chance, and status chance, making it one of the most versatile and effective primary weapons in the game.

This weapon excels in mid-to-long-range combat, allowing Tenno to pierce through enemies with ease. Its high-status chance makes it an excellent candidate for elemental builds, enabling players to strip armor or inflict status effects like Corrosive or Viral. The Boltor Prime’s accuracy and bolt travel speed make it particularly satisfying to use, as enemies are often pinned to walls upon death—a signature feature of the Boltor family.

While its critical stats are not as high as some other weapons, the combination of raw damage, status potential, and utility makes the Boltor Prime a reliable choice for both newcomers and seasoned players. It performs exceptionally well in missions with heavily armored enemies, thanks to its innate puncture damage.

The Boltor Prime can be obtained through relic farming or trading with other players. With its deadly precision and unique mechanics, this weapon remains a staple in many players’ arsenals and a standout among Warframe’s best Prime weapons.

#5: Akstiletto Prime

The Akstiletto Prime is an outstanding dual secondary weapon in Warframe, known for its exceptional fire rate, critical potential, and status chance. As the Prime variant of the Akstiletto, it boasts improved damage, critical stats, and a higher status chance, making it a versatile sidearm that excels in both crowd control and single-target damage.

This weapon’s high fire rate and accuracy allow players to rapidly shred through enemies, while its impressive status chance makes it perfect for inflicting elemental damage. Mods like Barrel Diffusion, Lethal Torrent, and Primed Pistol Gambit amplify its performance, turning it into a deadly tool for melting even the toughest foes.

The Akstiletto Prime’s balance of critical and status stats ensures its effectiveness in a variety of builds, whether you’re focusing on Viral damage for crowd clearing or Corrosive for tearing through armored enemies. Its lightweight design and fast reload speed also make it a joy to use in fast-paced missions.

You can acquire the Akstiletto Prime by farming its parts through relics or trading with other players. Its combination of speed, power, and versatility solidifies its position as one of the best Prime weapons in Warframe, and a must-have for any Tenno seeking a reliable secondary weapon.

#4: Tigris Prime

The Tigris Prime is a devastating shotgun in Warframe, renowned for its unparalleled burst damage and ability to annihilate even the most heavily armored enemies. As the Prime variant of the Tigris, it features enhanced base damage, critical chance, and status chance, making it one of the most powerful weapons in the game.

What sets the Tigris Prime apart is its unique double-barrel mechanic, firing two devastating shots per trigger pull. With its innate ability to inflict high-status procs and deal massive Slash damage, the Tigris Prime excels at quickly killing high-priority targets, making it ideal for bosses and endgame missions. Mods like Hunter Munitions and Primed Point Blank further amplify its destructive potential, while elemental combinations like Viral and Heat maximize its effectiveness against heavily armored foes.

Though the Tigris Prime has a slow reload speed and limited ammo efficiency, these drawbacks are easily offset by its incredible damage output. It’s a weapon designed for precision and impact, rewarding players who plan their shots carefully.

The Tigris Prime can be obtained by farming its parts through relics or trading with other players. Its overwhelming power and effectiveness in high-level content make it an essential addition to any Tenno’s arsenal, solidifying its place as one of the best Prime weapons in Warframe.

#3: Vasto Prime

The Vasto Prime is a sleek, revolver-style secondary weapon in Warframe, prized for its high critical chance, quick draw speed, and satisfying single-shot damage. As the Prime variant of the Vasto, it brings improved base damage, critical multiplier, and faster reload speed, making it a perfect choice for Tenno who favor precision and agility.

This weapon shines in critical-focused builds, with mods like Primed Pistol Gambit and Primed Target Cracker unlocking its full potential. Its high fire rate and accuracy make it ideal for quick headshots, while its stylish, gunslinger-inspired design adds a touch of flair to your Fashion Frame. The Vasto Prime excels in mid-range engagements, making it versatile across various mission types.

Though its magazine size is relatively small, the Vasto Prime’s fast reload speed ensures you’re always ready for the next shot. Its performance against unarmored and lightly armored enemies is stellar, and with the right elemental mods, it can hold its own in endgame missions.

You can acquire the Vasto Prime through relic farming or by trading with other players. Its combination of speed, power, and elegance cements it as one of the best Prime secondary weapons in Warframe and a must-have for any sharp-shooting Tenno.

#2: Paris Prime

The Paris Prime is a precision-focused bow in Warframe, known for its deadly single-shot damage and silent operation. As the Prime variant of the Paris, it boasts improved base damage, critical chance, and critical multiplier, making it one of the most powerful and versatile bows available in the game.

This weapon excels at eliminating enemies from a distance, with its pinpoint accuracy and exceptional critical stats enabling devastating headshots. When paired with mods like Point Strike, Vital Sense, and Hunter Munitions, the Paris Prime can deal massive critical and Slash damage, making it highly effective against both armored and unarmored targets. Its silent operation also makes it a great choice for stealth missions.

While its charge time requires a bit of planning, the sheer power of a fully charged shot more than compensates for the delay. The Paris Prime’s innate impact and puncture damage, combined with the ability to mod for elemental effects, ensure its viability in high-level content.

You can obtain the Paris Prime by farming its parts through relics or trading with other players. Its combination of precision, stealth, and raw power earns it a top spot among Warframe’s Prime weapons and a favorite for Tenno who value skillful marksmanship.

#1: Orthos Prime

The Orthos Prime is a standout melee weapon in Warframe, revered for its incredible range, speed, and versatility. As the Prime variant of the Orthos, it boasts enhanced attack speed, critical chance, and status chance, making it one of the most efficient and deadly polearms in the game.

Its exceptional reach allows Tenno to clear large groups of enemies with ease, making it a top-tier weapon for crowd control in missions like Survival and Defense. The Orthos Prime’s high critical stats pair perfectly with mods like Blood Rush and Condition Overload, enabling it to scale effectively into endgame content. Its speed ensures that every swing feels fluid and impactful, delivering consistent damage to even the toughest foes.

What sets the Orthos Prime apart is its balance of power and accessibility. It’s easy to mod for critical, status, or hybrid builds, making it adaptable to a variety of playstyles. Whether you’re carving through hordes of enemies or focusing on single-target damage, this weapon performs admirably in any scenario.

The Orthos Prime can be obtained through relic farming or trading with other players. With its unparalleled range, speed, and efficiency, it rightfully earns its place as the best Prime weapon in Warframe. It’s a must-have for any Tenno looking to dominate the battlefield with style and precision.

Conclusion

Prime weapons in Warframe are more than just upgraded versions of their standard counterparts—they represent the pinnacle of power, precision, and performance for any Tenno. Each weapon on this list stands out for its unique strengths, whether it’s the Orthos Prime’s unrivaled range and speed, the Tigris Prime’s devastating burst damage, or the Paris Prime’s silent precision. These weapons not only excel in combat but also enhance the overall experience of tackling Warframe’s toughest challenges.

Acquiring Prime weapons, whether through relic farming or trading, is an essential step for players aiming to maximize their arsenal and succeed in endgame content. With their enhanced stats and often stunning designs, Prime weapons embody the balance between style and functionality that Warframe is renowned for. Whatever your playstyle, there’s a Prime weapon to suit your needs and help you dominate the battlefield.