League of Legends Kha'Zix Guide: Best Build, Runes & Combos

Kha’Zix is a lethal assassin in League of Legends known for isolating targets and eliminating them with swift, burst damage. Whether you’re dominating the jungle or roaming for kills, Kha’Zix thrives on picking off enemies who stray too far from their team. In this guide, we’ll break down the best build, runes, items, and combos you need to master Kha’Zix and carry your games with brutal efficiency.

Kha’Zix Abilities Overview In League of Legends

Kha’Zix’s kit is built around isolation and evolution. His passive, Unseen Threat, empowers his next basic attack with bonus magic damage and a slow when he’s unseen by the enemy. His Q, Taste Their Fear, deals massive single-target damage, which is greatly increased if the target is isolated. His W, Void Spike, fires spikes in a line that explode on impact, healing Kha’Zix if he’s within the explosion radius. His E, Leap, lets him jump to a location, dealing damage on arrival and resetting on takedowns if evolved. Finally, his R, Void Assault, allows him to become invisible up to two times (three when evolved), giving him a window to reposition or escape while triggering his passive with each cast. Each ability can be evolved once, boosting its power and adding extra effects that dramatically enhance his assassination potential.

How To Play Kha’Zix In League of Legends

Best Summoner Spells For Kha’Zix

The best summoner spells for Kha’Zix are Smite and Flash. Smite is essential for clearing jungle camps and securing objectives like Dragon and Baron, while Flash gives you more flexibility for escaping bad fights or securing kills. If you’re confident and want to snowball hard, you can also take Ignite in certain matchups, but it’s a risky play that’s better suited for experienced Kha’Zix players in specific comps.

Best Runes For Kha’Zix

The best runes for Kha’Zix focus on maximizing his burst damage and snowball potential. For his primary tree, go Domination with Electrocute as the keystone to boost his assassination burst. Pair it with Sudden Impact for extra lethality after using Leap or Ult, Eyeball Collection for more AD scaling, and Relentless Hunter to roam and gank faster. For the secondary tree, go Inspiration with Magical Footwear and Cosmic Insight for free boots and faster cooldowns on Smite, Flash, and items like Prowler’s Claw. Take Adaptive Force, Adaptive Force, and Armor or Magic Resist in your stat shards depending on the matchup. This setup helps you delete squishies and control the jungle efficiently.

Best Build For Kha’Zix

The best build for Kha’Zix in League of Legends is centered around high burst damage and mobility to quickly eliminate priority targets. Start with Youmuu’s Ghostblade for early lethality and speed, then build Duskblade of Draktharr or Prowler’s Claw as your Mythic for extra burst and stealth or gap-closing power. Follow with Edge of Night for a spell shield and survivability, then Serylda’s Grudge for armor penetration and slow on abilities. Finish with Guardian Angel for teamfight insurance or Maw of Malmortius if you’re dealing with heavy AP threats. Boots-wise, grab Ionian Boots of Lucidity for ability haste or Plated Steelcaps/Mercury’s Treads for defense depending on the enemy team. This build gives you everything Kha’Zix needs to dominate solo picks and skirmishes.

Best Combos To Learn For Kha’Zix

The best Kha’Zix combos focus on quick burst and isolation damage to eliminate enemies fast. A basic engage combo is E (Leap) → Q (Taste Their Fear) → W (Void Spike) → Auto Attack, which works best when the target is isolated. For more burst, add R (Void Assault) either before or after your Leap to reduce vision and reposition. A great assassination combo would be R → E → Q → W → Auto, using your invisibility to get closer or dodge skillshots. You can also do W → E → Q from a distance to poke and finish off low-health enemies. Mastering when to evolve your abilities (usually Q first, then E or R) and using passive auto attacks between abilities will help you delete squishy targets and snowball hard.

Conclusion

Kha’Zix is a deadly assassin who thrives on isolating targets and picking them off one by one. With the right build, runes, and combos, you can dominate the jungle and control the pace of the game. Mastering his evolved abilities, smart positioning, and timing your engages will turn you into a constant threat across the map. Stick to his strengths—burst damage, mobility, and vision control—and you’ll quickly climb the ranks as a true predator.