Vex is a powerful mid lane mage in League of Legends who specializes in punishing dashes and diving into team fights with burst damage. Her kit is built around fear, poke, and quick burst combos that can delete squishy targets in seconds. Whether you’re looking to climb the ranks or just frustrate mobile champions, mastering Vex’s mechanics and itemization is key. In this guide, we’ll cover the best build, runes, items, and combos to help you dominate the mid lane with Vex.
Vex’s abilities are designed to punish mobile champions and deal consistent magic damage with crowd control. Her passive, Doom ‘n Gloom, empowers her next basic ability to fear enemies and enhances damage against enemies who recently dashed. Her Q, Mistral Bolt, fires a straight-line missile that deals damage to all enemies hit, perfect for poke and wave clear. Her W, Personal Space, is an AoE shield that damages nearby enemies—great for trading and surviving burst. Her E, Looming Darkness, sends a slow-moving shadow that explodes on impact, applying Gloom and slowing enemies. Finally, her R, Shadow Surge, is a long-range dash-and-execute ability that marks the first enemy hit. If the target dies shortly after, Vex can recast it, making it deadly in teamfights. Mastering how to layer her fear and burst combo is key to dominating with Vex.
The best summoner spells for Vex are Flash and Teleport. Flash gives Vex the mobility she lacks, helping her reposition during fights or escape danger. Teleport is ideal for map presence, allowing her to return to lane quickly or make game-changing plays in side lanes and teamfights. If you’re facing aggressive assassins or need more safety, you can swap Teleport for Barrier or Exhaust to survive early-game threats.
The best runes for Vex in League of Legends focus on burst damage, survivability, and lane control. Take Electrocute as your keystone from the Domination tree for quick burst combos. Pair it with Taste of Blood for sustain, Eyeball Collection for AP scaling, and Ultimate Hunter to reduce the cooldown of her game-changing R. In the secondary tree, go Sorcery with Manaflow Band to manage her mana issues and Transcendence for cooldown reduction. For minor runes, use Adaptive Force, Adaptive Force, and Magic Resist or Armor based on lane matchup. This setup gives Vex the ability to pressure lane, scale into teamfights, and blow up key targets efficiently.
The best build for Vex focuses on maximizing burst damage while giving her enough utility to stay safe and impactful in fights. Start with Luden’s Companion for instant burst and poke. Follow it with Sorcerer’s Shoes for magic penetration. Next, go for Shadowflame to shred through shields and boost damage. Then pick up Zhonya’s Hourglass for survivability, especially when diving in with your ult. After that, Rabadon’s Deathcap massively boosts your AP scaling, and Void Staff helps against enemies stacking magic resist. This build gives Vex everything she needs to blow up squishies and carry fights.
The best combos to learn for Vex focus on her burst potential and fear mechanics. The standard trade combo is E → Q—use Looming Darkness (E) to mark the enemy and slow them, then follow up immediately with Mistral Bolt (Q) to hit both parts of the skill and trigger Fear. For an all-in, use R → E → Q → W—cast Shadow Surge (R) to engage, then land E mid-air to mark and fear the target, hit Q for damage, and use Personal Space (W) when in range to deal AOE damage and shield yourself. In teamfights, wait for an enemy to be isolated or low, hit R, and reset it by getting a takedown. This allows Vex to chain ults across the backline and wipe teams if timed well
Vex is a powerful control mage that thrives on catching enemies off guard with her burst and crowd control. With the right build and runes, she can dominate the mid lane and swing teamfights in your favor. Learning her combos and positioning well lets you fully take advantage of her reset potential and fear mechanics. Whether you’re looking to climb ranked or just enjoy explosive mid-lane gameplay, mastering Vex gives you the tools to carry your games with confidence.
Posted On: June 19th, 2025
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