League of Legends Lissandra Guide: Best Build, Runes, Items, Combos

Lissandra is a powerful control mage in League of Legends known for her crowd control, team fight presence, and ability to dive into fights without fear thanks to her self-cast ultimate and slippery mobility. Whether you’re locking down enemy carries, engaging with Frozen Tomb, or using her AoE slows to control the battlefield, Lissandra thrives in chaotic skirmishes and objective fights. In this guide, you’ll find the best build, runes, items, and combos to maximize her impact in any matchup and dominate the mid lane.

Lissandra Abilities Overview

Passive – Iceborn Subjugation: When a champion dies near Lissandra, their body becomes a Frozen Thrall. After a brief delay, the thrall reanimates and slowly chases nearby enemies before exploding, dealing magic damage in an area. This makes her team fights extremely punishing and allows her to zone enemies effectively.

Q – Ice Shard: Lissandra hurls a spear of ice that shatters when it hits a target, dealing magic damage and slowing enemies. If it hits an enemy, it continues through them, damaging other enemies in its path. This ability is great for poke, wave clear, and consistent slows.

W – Ring of Frost: Instantly damages and roots all enemies around her. This is a strong peel and crowd-control tool, allowing Lissandra to trap enemies who get too close or stop dashes and dives instantly.

E – Glacial Path: Sends a claw of ice in a straight line that damages enemies it passes through. Lissandra can reactivate the ability to blink to the claw’s current position. This gives her excellent engage, mobility, and escape potential.

R – Frozen Tomb: Can be cast on herself or an enemy champion. If cast on herself, she becomes untargetable and heals while damaging and slowing enemies around her. If cast on an enemy, it stuns them and creates a damaging zone of ice. It’s a powerful tool for both self-survival and team fight initiation.

Best Summoner Spells For Lissandra

The best summoner spells for Lissandra in League of Legends are Flash and Teleport. Flash is essential for repositioning during engages, escaping ganks, or making quick plays with her E + Flash combo. Teleport is ideal for returning to lane quickly, joining skirmishes across the map, or applying split push pressure while still being able to assist in team fights. For more aggressive matchups or snowballing potential, Ignite can be used instead of Teleport to secure kills and apply healing reduction, especially against champions with sustain.

Best Runes For Lissandra

The best runes for Lissandra in League of Legends focus on enhancing her crowd control, lane pressure, and teamfight presence. Here’s a strong and meta-optimized rune setup:

Primary – Domination (Electrocute):
• Electrocute: Adds burst damage to her quick combos, perfect for assassinating squishy targets.
• Cheap Shot: Synergizes with her crowd control by dealing bonus true damage to impaired enemies.
• Eyeball Collection: Increases her AP as she gets takedowns, helping her scale into mid and late game.
• Ultimate Hunter: Reduces the cooldown on her R, allowing for more frequent game-changing ults.

Secondary – Inspiration:
• Perfect Timing: Gives a free Stopwatch for safer dives and tower dives, and helps set up aggressive Flash + R plays.
• Cosmic Insight: Grants cooldown reduction on summoner spells and items, making Flash and Stopwatch more available.

Stat Shards:
• Adaptive Force
• Adaptive Force
• Health or Magic Resist (based on matchup)

This rune page gives Lissandra strong early burst, great utility, and better teamfight uptime, making it ideal for most matchups.

Best Build For Lissandra

The best build for Lissandra in League of Legends focuses on burst damage, utility, and survivability. Start with Doran’s Ring and a Health Potion for early lane control. Your first core item should be Luden’s Companion for burst damage and mana sustain. Follow this with Zhonya’s Hourglass, which synergizes with her all-in engage and allows her to dive safely with Frozen Tomb. For boots, go with Sorcerer’s Shoes to boost magic penetration. After that, build Shadowflame to amplify burst against shielded or squishy targets. Rabadon’s Deathcap is a great late-game power spike for raw AP scaling. Finish the build with Void Staff if the enemy team stacks magic resist, or Morellonomicon if you need Grievous Wounds. This setup gives Lissandra strong burst, utility, and survivability for teamfights and skirmishes.

Best Combos To Learn for Lissandra

Here are the best combos to learn for Lissandra to maximize her burst and crowd control:

1. Basic Poke Combo:
E → Q → W
Use Glacial Path (E) to close the gap, then immediately Q (Ice Shard) and W (Ring of Frost) to poke and root the enemy. This is your bread-and-butter harass combo in lane.

2. All-in Combo (Pre-6):
E → Flash → W → Q
Cast E, then Flash right before it lands to reposition and instantly root the enemy with W, followed by Q. Great for surprising opponents and securing early kills.

3. Full Combo (Level 6+):
_E → R → W → Q → Auto Attacks**
Initiate with E, cast R (Frozen Tomb) on the enemy or yourself depending on the situation, then W and Q for burst damage. Follow up with autos if safe.

4. Safe Engage:
_E → R (self-cast) → W → Q**
If you’re diving into multiple enemies, use R on yourself for healing and stasis while CCing nearby enemies. Then W to root and Q for damage as soon as you’re active again.

5. Instant Engage Combo:
_Flash → W → R → Q → E (away)**
Great for catching carries off guard. Flash in and root with W, immediately R the target, Q for damage, then E away for a safe exit if needed.

Mastering these combos will make you a much more effective teamfighter, roamer, and playmaker with Lissandra.

Conclusion

Lissandra is a powerful mid lane control mage who thrives in teamfights and excels at locking down priority targets. With the right runes, items, and combos, she can quickly burst squishier enemies while also providing valuable crowd control and zone denial for her team. Whether you’re looking to dominate lane with quick trades or become your team’s main engage tool in late-game fights, mastering her toolkit will make you a serious threat on the Rift.